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Week 13 is here, headlined by the highly-anticipated rematch of last year's NFC Championship game.Yes, you read that correctly. In an early holiday present, the and will meet in a contest that very well may contain Ian Desmond Jersey the winner of Super Bowl LVIII .Elsewhere on the docket, we have an interesting matchup in , where the will be visiting with an eye on concocting a victory amid many injuries. Can this hobbled squad get their first win against the AFC North this season?I went 4-0 last week on my outright picks, bringing my season total to 38-25-1.ADVERTISEMENT Let's keep this thing rolling!Without further ado, here are my best bets for Week 13.(All times ET)49ers @ Eagles (4:25 p.m. Sunday, FOX and FOX Sports app)Ive been ranting about this game since the line came out, and Ive bet San Francisco all week. When they were -1, -1.5, -2, and -2.5. Im pa sing at the key number of 3.The 49ers have had this game circled for months after the NFC title game lo s when left in the first quarter with an arm injury. Theyre healthy and have been dominating since that unlucky three-game skid that included a mi sed FG at the horn in and injuries to Purdy (concu sion), and the following two weeks.FINAL SF 42 PHI 19 NFL SPREADTO WINTOTAL San Francisco 49ers SF -3.0 -158 O 46.5 Philadelphia Eagles PHI +3.0 +134 U 46.5 The Eagles have been outgained by 100+ yards in the last four games and fell into deep holes the last two weeks, only to have rally them to improbable victories.After the MNF win in , they had a short week to prepare for , in which the defense was on the field for 92 plays Bryan Shaw Jersey in an overtime win.It would not surprise me at all if San Francisco jumped to an early lead and choked out Philly by two touchdowns.PICK: San Francisco (-2.5) to win by more than 2.5 pointsPICK: San Francisco 1st half moneyline (-148)PICK: San Francisco TT Over 24.5 pointsWill Brock Purdy, 49ers overwhelm Jalen Hurts, Eagles? Cardinals @ Steelers (1 p.m. Sunday, CBS)For reasons I cant fully explain, Chris Iannetta Jersey I cant quit the Steelers.This is exactly the spot Mike Tomlin struggles in home favorite against a bad team and Pittsburgh has a short week before a game against the hated New England Patriots on Thursday.If the Steelers are up two touchdowns in the second, does Tomlin pull in the oars and hope he can just coast to victory?FINAL ARI 24 PIT 10 NFL SPREADTO WINTOTAL Arizona Cardinals ARI +6.0 +224 O 41 Pittsburgh Steelers PIT -6.0 -280 U 41 Arizona is struggling with injuries to wide receivers and . In addition, tight end mi sed practice Wednesday, and its unclear if he will play.The Steelers defense gets a boost with All-Pro safety back, and as long as Pittsburgh can have some red zone production (1-for-4 last week; 28th in the NFL this season), they get margin for the cover.PICK: Steelers (-5.5) to win by more than 5.5 pointsRyan Shazier on Kenny Pickett, Pittsburgh Steelers' outlook for rest of season Panthers @ Buccaneers (4:05 p.m. Sunday, CBS)The Panthers are a league-worst 1-8-2 against the spread, while Tampa has been a profitable 7-4. But a closer look reveals the Bucs have only been favored twice, losing outright to 16-13 and then beating rookie quarterback last month.FINAL CAR 18 TB 21 NFL SPREADTO WINTOTAL Carolina Panthers CAR +3.5 +167 O 37 Tampa Bay Buccaneers TB -3.5 -200 U 37 Now theyre playing as nearly a touchdown favorite with a QB who dinged up his ankle last week and had an MRI?Oh, and the defense will likely be without linebacker again. If that wasn't enough, mi sed practice Thursday, and cornerback may sit again.When you to s in the head coach bump and all the new run-play options will be running, you Scott Oberg Jersey might want to sprinkle a little on the money line.PICK: Panthers (+6) to lose by 6 points or fewer (or win outright)Blazin' 5: 49ers avenge Eagles, Jets upset Falcons in Colin's Week 13 picks Colts @ Titans (1 p.m. Sunday, CBS)Theres not much to like about the Titans this year unle s theyre playing at home, where the Titans are 4-0 straight up and 4-0 ATS.The Colts have become popular with bettors, having won and covered the last three as small favorites. Rookie coach Shane Steichen has been incredible and aggre sive, but lets see if any of that changes with the injury to .FINAL / OT IND 31 TEN 28 NFL SPREADTO WINTOTAL Indianapolis Colts IND -1.5 -123 O 42 Tenne see Titans TEN +1.5 +103 U 42 Mike Vrabel had won five straight against the Colts before losing 23-16 this season, but was starting at QB and the Titans DL run-stopper was out. also rushed for 165 yards, and he wont do that again.PICK: Titans (+1) to lose by a point (or win outright)Jason McIntyre is a FOX Sports betting analyst who also writes about the NFL and NBA Draft. Before arriving at FOX Sports, he created the Trevor Story Jersey website The Big Lead. Follow him on Twitter @JasonRMcIntyre. 
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